Efficient and precise delivery of CRISPR/Cas9 components remains one of the critical challenges toward the advancement of gene-editing therapies. Here, we have developed a high-throughput Barcode-Integration Nanoparticle Screen (BINS) method to evaluate a library of 96 lipid nanoparticles (LNPs) for their delivery efficiency across  in vitro  and  in vivo  models.  

This paper falls within the fields of medical mycology, immunology, and vaccinology, specifically addressing the emerging application of mRN

DOTMA vs. DOTAP lipid nanoparticles for GFP expression on human PBMCs and THP-1 cell line Authors:  Erwin Pavel Lamparelli, Elena...

This paper sits at the intersection of pharmaceutical technology, nanomedicine, and RNA therapeutics – fields that have gained tremendous at

Microfluidic Monodispersed Microbubble Generation Droplet

Authors: César Palacios-Arias, Marc Jofre, María-José López, Youness Akazzim, Lluis Jofre, Jordi Romeu, and Luis Jofre-Roca César...

Authors: Kai Chen, Hesong Han, Sheng Zhao, Bryant Xu, Boyan Yin, Atip Lawanprasert, Marena Trinidad, Benjamin W. Burgstone, Niren Murthy,...

The paper "Applications of Microfluidics in mRNA Vaccine Development: A Review" by Ali Fardoost and colleagues, published in...

PLA/PLGA nanocarriers have emerged as promising vehicles for drug delivery, offering controlled release and targeted therapeutic...

Author: Eunice I. Aissi Thesis Supervisor: Tonio Buonassisi Abstract Materials development is the foundation for innovation in many...

Authors: Qiyan Wang, Ting Su, Furong Cheng, Shurong Zhou, Xiang Liu, Mi Wang, Ri Tang, You Xu, Shimiao Liao, Jordan Dailey, Guolan Xiao,...

Authors: Mohammed A. Al-Qadasi, Samantha M. Grist, Matthew Mitchell, Karyn Newton, Stephen Kioussis, Sheri J. Chowdhury, Avineet...

Authors: Xiaoxia Chen, Yongfeng Ye, Mengrong Li, Taisen Zuo, Zhenhua Xie, Yubin Ke, He Cheng, Liang Hong, and Zhuo Liu Abstract Lipid...

Authors: Xiangyang Wang, Ruojiang Wang, Yuyang Zhang, You Wu, Xu Wu, Zihao Luo, Yu Chang, Xiansheng Zhang, and Tingrui Pan Abstract...

Authors: Liang Hu, Shiming Zhang, John Sienkiewicz, Hua Zhou, Robert Berahovich, Jinying Sun, Michael Li, Adrian Ocampo, Xianghong Liu,...

Authors: Nina Erwin, Umasankar De, Yufeng Xiao, Lei Wang, Chandra Maharjan, Xiaoshu Pan, Nikee Awasthee, Guangrong Zheng, Daiqing Liao,...

Lipid nanoparticle-encapsulated DNA vaccine confers protection against swine and human-origin H1N1 influenza viruses Authors: The N....

Authors: Noah James Langenfeld and Bruce Bugbee Abstract Here we review the 400-year history of hydroponic culture and describe a unique...

Authors: Simona Plesselova, Kristin Calar, Hailey Axemaker, Emma Sahly, and Pilar de la Puente Abstract The majority of ovarian cancer...

Authors: Jian Yu, Wei Cheng, Jinchun Ni, Changwu Li, Xinggen Su, Hui Yan, Fubing Bao, and Likai Hou Abstract This work reports a simple...