Max-Planck-Institut für Kohlenforschung: New study reveals stereochemistry of lipid nanoparticles critically influences safety and efficacy in mRNA delivery Nagoya University: Japanese researchers engineered a new lipid nanoparticle that delivers mRNA to cells five times more effectively using cyclic disulfide modifications University of Pennsylvania: Study unlocks safer RNA therapies by reducing harmful inflammation caused by lipid nanoparticles using biodegradable lipids

Nagoya University: New cyclic disulfide lipids deliver mRNA five times more effectively for cancer treatment University of Ottawa: Development of nano-sized delivery agents with therapeutic potential beyond messenger function University of Pennsylvania: Chemical modification of ionizable lipids reduces inflammation and boosts mRNA therapeutic effectiveness Academic Journals: Multiple publications on circular guide RNA engineering, CRISPR-Cas13d systems, and advanced LNP ch

AbbVie: acquires Capstan Therapeutics for up to $2.1 billion, adding targeted LNP (tLNP) in vivo CAR-T technology to its immunology pipeline. CRISPR Therapeutics: Phase 1 data show LNP-delivered CRISPR candidate CTX310 cuts triglycerides and LDL by up to 82% and 86%, respectively. University of Pennsylvania–Genevant (Nature Nanotechnology): PEG-lipid ratio and phospholipid choice fine-tune mRNA-LNP adjuvanticity, guiding vaccine design. Ludwig-Maximilians-Universität Münch

Eli Lilly: Acquired Verve Therapeutics for up to $1.3 billion to advance LNP-based gene editing therapies for cardiovascular disease. Genprex: Presented research on non-viral diabetes gene therapy using lipid nanoparticle delivery system at the American Diabetes Association conference. SNS Insider: Published market report projecting lipid nanoparticles market to reach $2.89 billion by 2032, driven by mRNA technology advances. Nature Nanotechnology: Published study on tailo

Cornell University: Developed PEG-free "stealth" LNPs to reduce immune responses in mRNA vaccines. University of Hawaiʻi/Sungkyunkwan University: Created neutrophil-targeted LNPs to mitigate COVID-19 lung damage. Moderna: Received FDA approval for next-gen COVID-19 vaccine (mNEXSPIKE) using refrigerated LNPs. CRISPR Therapeutics: Reported positive Phase 1 data for LNP-delivered ANGPTL3 gene-editing therapy. University of Pennsylvania: Enhanced T-cell responses in mRNA vac

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Innorna: Presented new data on mRNA-LNP therapies for PFIC2 and Wilson’s Disease at ASGCT 2025. University of Nottingham, MIT, Sail Biomedicines: Developed cryogenic mass spectrometry to analyze LNP surface structures. Sail Biomedicines: Announced preclinical data on in vivo eRNA CAR-T candidate SAIL-0804 for autoimmune diseases. Arcturus Therapeutics: SWOT analysis highlighted LNP platform advancements and pipeline progress. ResearchAndMarkets.com: Reported mRNA platform

Mana.bio: Presented new data demonstrating AI-driven safety model for lipid nanoparticle tolerability to enhance RNA medicine. Grit Biotechnology: Presented scientific breakthroughs at ASGCT 2025 including LNP-mediated CRISPR/Cas9 gene editing for enhancing tumor-infiltrating lymphocytes. Generation Bio: Reported business highlights including advancement of their cell-targeted lipid nanoparticle (ctLNP) technology for siRNA delivery. Aera Therapeutics: Shifted focus

StatNano/Grand View Research: A new market report forecasts the global lipid nanoparticle market to reach $1.54 billion by 2030, growing at a CAGR of 13.64%, driven by increased demand for innovative drug delivery solutions. SyVento BioTech: SyVento BioTech participates in the World Vaccine Congress in Washington, D.C., showcasing their expertise in lipid-based nanocarriers and LNP technology for pharmaceutical products including RNA-based drug products. Arbor Biotechno

Arbor Biotechnologies: Unveiled FDA approval of an IND filing for their LNP-mediated treatment for primary hyperoxaluria type 1. Rothwell Figg (Dan Shores): Led a workshop on intellectual property challenges for LNP-based therapies at the LNP Summit. NOF CORPORATION: Presented biodegradable LNPs with tunable immunogenicity for vaccine and gene therapy applications. Serina Therapeutics: Introduced immune-silent POZ-lipid technology as a PEG alternative for LNPs at the

University of Pennsylvania: Developed nitro-oleic acid-modified LNPs for safer plasmid DNA delivery, enabling long-term gene expression in mice. ACS Biochemistry Study: Introduced click chemistry LNPs for targeted mRNA delivery to metabolically labeled cancer cells. Marama Labs: Launched CloudSpec, a tool for rapid lipid nanoparticle analysis, reducing lab times from hours to seconds. Global Market Report: Projected lipid nanoparticle market growth to US$2.39 billion by 20

Sanofi: Published research in Nanoscale on optimizing PEGylated lipids for enhanced mRNA delivery efficacy and stability. University of

Serina Therapeutics: Presented preclinical data on non-immunogenic POZ-lipid technology at the ACS Spring 2025 Meeting. Genevant Sciences an

Frontiers in Nanotechnology: Published research article on RNA-lipid nanoparticle therapeutics for women's health, focusing on gynecological

News Summary Nature: Published research on fabrication of mRNA encapsulated lipid nanoparticles using SMART-MaGIC technologies. Clinical P

Summary of Recent LNP News Johns Hopkins Institute for NanoBioTechnology: Developed a machine learning model to predict efficient lipid nano

Section 1: Brief Summary of News Nature: Published research on improving safety of lipid nanoparticle-based DNA delivery by incorporating

1. Arbutus Biopharma Appoints New CEO and Restructures Board to Prioritize LNP Technology Release Date : February 25, 2025 Source :...