Hepatocellular carcinoma (HCC) represents the second leading cause of cancer-related mortality worldwide, claiming over 700,000 lives annually. The liver's central role in blood filtration and metabolism makes it an attractive target for drug delivery, with lipid nanoparticles (LNPs) showing particular promise due to their natural hepatic tropism. However, LNP efficacy becomes compromised in HCC environments due to inadequate understanding of liver physiology under cancerous

Max-Planck-Institut für Kohlenforschung: New study reveals stereochemistry of lipid nanoparticles critically influences safety and efficacy in mRNA delivery Nagoya University: Japanese researchers engineered a new lipid nanoparticle that delivers mRNA to cells five times more effectively using cyclic disulfide modifications University of Pennsylvania: Study unlocks safer RNA therapies by reducing harmful inflammation caused by lipid nanoparticles using biodegradable lipids

Nagoya University: New cyclic disulfide lipids deliver mRNA five times more effectively for cancer treatment University of Ottawa: Development of nano-sized delivery agents with therapeutic potential beyond messenger function University of Pennsylvania: Chemical modification of ionizable lipids reduces inflammation and boosts mRNA therapeutic effectiveness Academic Journals: Multiple publications on circular guide RNA engineering, CRISPR-Cas13d systems, and advanced LNP ch

We’re excited to announce that PreciGenome will be exhibiting at the CRS 2025 Annual Meeting & Exposition! Join us at booth #406 to discover our latest innovations in lipid nanoparticle (LNP) technology. What we offer: Advanced LNP synthesis instruments for efficient and reproducible nanoparticle production High-quality LNP reagents to support your research and development Comprehensive CRO services tailored for your LNP and drug delivery projects Connect with our

AbbVie: acquires Capstan Therapeutics for up to $2.1 billion, adding targeted LNP (tLNP) in vivo CAR-T technology to its immunology pipeline. CRISPR Therapeutics: Phase 1 data show LNP-delivered CRISPR candidate CTX310 cuts triglycerides and LDL by up to 82% and 86%, respectively. University of Pennsylvania–Genevant (Nature Nanotechnology): PEG-lipid ratio and phospholipid choice fine-tune mRNA-LNP adjuvanticity, guiding vaccine design. Ludwig-Maximilians-Universität Münch

Eli Lilly: Acquired Verve Therapeutics for up to $1.3 billion to advance LNP-based gene editing therapies for cardiovascular disease. Genprex: Presented research on non-viral diabetes gene therapy using lipid nanoparticle delivery system at the American Diabetes Association conference. SNS Insider: Published market report projecting lipid nanoparticles market to reach $2.89 billion by 2032, driven by mRNA technology advances. Nature Nanotechnology: Published study on tailo

Cornell University: Developed PEG-free "stealth" LNPs to reduce immune responses in mRNA vaccines. University of Hawaiʻi/Sungkyunkwan University: Created neutrophil-targeted LNPs to mitigate COVID-19 lung damage. Moderna: Received FDA approval for next-gen COVID-19 vaccine (mNEXSPIKE) using refrigerated LNPs. CRISPR Therapeutics: Reported positive Phase 1 data for LNP-delivered ANGPTL3 gene-editing therapy. University of Pennsylvania: Enhanced T-cell responses in mRNA vac

We're proud to share that the Mayo Clinic Florida’s new RNA Research Facility has chosen the PreciGenome NanoGenerator™ Flex-S as their...

Mana.bio: Presented new data demonstrating AI-driven safety model for lipid nanoparticle tolerability to enhance RNA medicine. Grit Biotechnology: Presented scientific breakthroughs at ASGCT 2025 including LNP-mediated CRISPR/Cas9 gene editing for enhancing tumor-infiltrating lymphocytes. Generation Bio: Reported business highlights including advancement of their cell-targeted lipid nanoparticle (ctLNP) technology for siRNA delivery. Aera Therapeutics: Shifted focus

StatNano/Grand View Research: A new market report forecasts the global lipid nanoparticle market to reach $1.54 billion by 2030, growing at a CAGR of 13.64%, driven by increased demand for innovative drug delivery solutions. SyVento BioTech: SyVento BioTech participates in the World Vaccine Congress in Washington, D.C., showcasing their expertise in lipid-based nanocarriers and LNP technology for pharmaceutical products including RNA-based drug products. Arbor Biotechno