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Microfluidic chips for in vitro paracrine signaling

Case Western Reserve University explores multiplexed microfluidic chip for cell co-culture to regulate paracrine signaling.


Paracrine signaling is a form of cellular communication essential to numerous biological processes including wound healing and tissue homeostasis.


This study discusses the potential microfluidic chips offer in addressing and solving challenges surrounding paracrine signaling as well as the limitations.


The group developed a co-culture chip designed to overcome these limitations during in vitro studies. PreciGenome's bubble trap (PG-BT-STD25UL) was incorporated into this design for culture media delivery for long-duration experiments.



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