PG-MFC Microfluidic Pump System

with pulse-free pressure/vacuum and flow control 

Microfluidic pump is a tool with the capability of accurately manipulating fluid in minute volume below the microliter/nanoliter range. Usually, a microfluidic pump includes a micropump and a pressure or flow controller in the same device.
 
Our PG-MFC microfluidic pump system with pressure/flow control system controller provides pulse-free precise positive and negative pressure. Stable constant flow rates can be set and controlled when used in conjunction with external liquid flow sensors. The microfluidic pressure pump system operates in a wide range with fast response time and accuracy.
 
The control software provides user-friendly interface with an integrated touch screen. No external computer is needed even for complicated process configuration. Internal pressure/vacuum pumps are included in the instrument as well. Meanwhile, external pressure source also can be used by Luer lock connection to our system.

8channel outputs

Pulse-free flow control with liquid flow sensors

Intuitive UI on 10" touch screen

Highly integrated system with internal pumps, digital IOs, pinch valve ports, rotary valve ports, etc.

System Benefits:

 
One touch and walk away
Python, C/C++, LabVIEW API
  • Integrated system with PC, software, pumps, valve control, digital IOs, etc​​​

  • Precise and accurate pressure/flow output

  • Fast response time

  • Controllable flow rate output with flow sensors

  • Luer lock standard connection. Easy connect to our reservoirs kits

  • No external pressure source required (can be connected to an external pressure source for higher pressure)

  • No external computer required

  • Research collaboration, custom design & OEM service available

  • Compatible with our pinch valves, isolation valves, rotary valves and PG high-speed imaging system

Cost effective
Internal pumps, IOs, valve control ports
Highly Integrated w. embedded PC & touchscreen 

Integrated Software:​

  • Simple and advanced work modes meet all your needs
  • Integrated touch screen with intuitive GUI
  • Plug & play
  • One-click to run the experiment
  • Easy setup for complex timing control with IO ports, digital trigger, external valves, cameras, liquid flow sensors
  • Compatible with our selector / switching rotary valves, pinch / isolation valves,  high-speed imaging system, and other accessories
GUI for simple operation and complex timing control
GUI for real-time sensor data (pressure/ flow rate) monitoring
 
 
PG-MFC pump system is more than a simple pump or controller. 

System Specifications:

​​​

  • Pressure sensor accuracy of ±0.25 %FSS BFSL (Full-Scale Span Best Fit Straight Line), sensor resolution: 0.0061 %

  • Pressure stability: 0.05 %

  • Flow rate repeatability: below 1% of the measured value

  • Highest sensitivity down to <1 µl/min

  • Maximum flow rate for water-based liquids: 10 ml/min;

  • ​Maximum flow rate for hydrocarbons: 80 ml/min​

Typical Setup Examples of PreciGenome Microfluidic Pressure Pump System 

Simple Setup Illustration

1. Reagents are loaded in microfluidic reservoir tubes.

 

There are two ports available on the reservoir cap. One is the Luer lock connector which connects pressure source from the PreciGenome microfluidic controller. The other port is for reagent tubing, one side of which dips into the reagent and the other side of which connects to the inlet of a microfluidic chip.

 

The gas tubing connects the reagent reservoir and the pressure controller integrated pressure pumps inside. The reagent tubing connects the reagent reservoir and the microfluidic chip. 

 

Users need to make sure the connection and fittings are airtight. 

2. Set up the pressure controller properly for your experiment. Start running the controller by simply clicking the run button on the touch screen.

 

When the controller provides positive pressure, reagents in tubes are pushed to flow through reagent tubings into microfluidic channels and then flow out to the waste.

Complex Setup Example of 28 Reagents Selection and Delivery System

The system consists of one PG-MFC controller, three rotary/select valves, one flow sensor, one microfluidic chip stage with a temperature control unit, one unit (bubble trap), and several reagent reservoirs.

 

The entire system is controlled either directly the GUI on PG-MFC controller, or by python scripts through the serial port on the PG-MFC controller.

Up to 10 samples/reagents can be connected to one rotary valve. In the schematics below, three rotary valves are connected in series. Up to 28 reagents can be randomly selected to flow into a microfluidic chip.

 

A flow sensor is connected between the microfluidic chip and the third rotary valve. The flow rate is monitored by the flow sensor. Users can set flow rates and PG-MFC controller is capable of controlling the flow rate through the feedback loop.

 

Sample selection is controlled by rotary valve switching.

 

The microfluidic chip is fixed on a stage with the temperature control unit, which can be controlled by PG-MFC controller as well. Users can set the desired flow rate, injection volume of a specific sample, desired temperature through the GUI on the PreciGenome microfluidic controller.

Applications of PreciGenome Microfluidic Pump System

droplets_small_size.jpg
cell_encapsulation_in_droplet_1.jpg
cells.JPG

More Applications:

 
 

New Release

Low-cost Solution

PG-MFC-LT light version​

  • High quality 

  • Low cost

  • 2 independent channels

  • Free software (Need an extra computer to run)

PG-MFC OEM version​

  • Custom design & OEM

  • Low cost

  • 2 independent channels and flow control with external flow sensors

  • Free software (Need an extra computer to run)

 
 

Some of Our Customers

Precigenome LLC | 2176 Ringwood Ave. San Jose, CA, 95131, USA

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