Cas9 mRNA (Cap1, 5-moUTP)
 
This Cas9 mRNA is used together with a purified guide RNA (gRNA) to direct site-specific recognition and cleavage of target genomic DNA in CRISPR-Cas genome editing systems.
 
Designed for efficient in vitro transfection, PreciGenome’s Cas9 mRNA provides a high-quality, ready-to-use alternative to plasmid- or protein-based Cas9 delivery. Its Cap1-capped, poly(A)-tailed, 5-moUTP-modified design supports high translation efficacy while minimizing innate immune activation — a research-grade tool for CRISPR-Cas9 genome editing, gene knockout, and functional gene-editing studies.
 
Product Features
Cap1 structure for enhanced translation efficiency.
5-moUTP modified nucleotide to reduce innate immune activation and enhance mRNA stability.
Poly(A) tail for stable expression and enhanced translation initiation.
 
Product Specifications
Form: Liquid
Concentration: 1 mg/mL
mRNA Length: 4548 nucleotides
Buffer: 1 mM Sodium Citrate, pH 6.4
Storage: Store at –40 °C or below.
Shipping Method: Dry ice
 
Quality Control
Appearance: Colorless liquid
RNA Purity: ≥ 95% (agarose gel electrophoresis)
OD260/OD280: 1.70–2.30
Endotoxin: < 10 EU/mg
pH: 6.0–7.0
For research use only.

Contact us for custom formulations or special requests.