LipidFlex™ 脂质纳米颗粒和脂质体制剂
Access advanced organ-on-chip models powered by PreciGenome microfluidic technology to generate human-relevant in vitro data for efficacy, safety, and mechanism-of-action studies.
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Human-relevant microphysiological models with dynamic perfusion and controlled shear stress
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Long-term cultures for chronic dosing, toxicity, and disease progression studies
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Flexible CRO partnerships: standard assays or fully custom studies
Why Organ-on-Chip Services from PreciGenome?
PreciGenome's organ-on-chip services combine our proven microfluidic pressure and flow controllers with advanced OOC membrane chips to recreate physiologically relevant in vitro models. By partnering with our CRO team, you can leverage organ-on-chip technology without investing in equipment, infrastructure, or in-house assay development.
Human-Relevant Microenvironments
Dynamic perfusion, controlled shear stress, and barrier functions to better mimic in vivo conditions.
Validated Microfluidic Platform
iFlow controllers and organ-on-chip membrane chips optimized for long-term perfusion and stable culture.
Flexible Engagement Models
From feasibility screens to multi-endpoint, multi-organ studies, tailored to your pipeline needs.
实验数据：
We offer standard study frameworks based on our established organ-on-chip configurations, as well as fully customized models and assays.
Efficacy & Mechanism Studies
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3D perfused tissue evaluation (liver, lung, tumor-on-chip)
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Functional readouts & biomarker release
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Morphological changes over time
Safety & Toxicity Assessment
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Long-term exposure & repeat-dose studies
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Continuous perfusion & media recirculation
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Viability, barrier integrity, cytokine release
ADME & Transport Studies
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Membrane chips with apical/basal perfusion
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Small molecule transfer & permeability
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Organ barrier modeling
Custom Model Development
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New organ-on-chip models & disease phenotypes
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Custom endpoints & chip configurations
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Integration of preferred cell sources & biomarkers
Service Workflow
Define scientific objectives, target organs, cell sources, endpoints, timelines, and budget.
2. Model & Assay Design
Select existing configuration or specify custom design with flow conditions
3. Experiment Execution
Chip preparation, seeding, perfusion control, dosing, and sampling
4. Data Analysis and Reporting
Collect quantitative data and perform statistical analysis. Comprehensive study report, raw data, and recommendations
Example Applications
Our organ‑on‑chip services support a wide range of applications across drug discovery, safety assessment, and translational research. By combining precisely controlled microfluidic perfusion with advanced organ‑specific and barrier models, these platforms enable more human‑relevant insights than traditional static cell culture. Researchers can use our models to evaluate efficacy, investigate mechanisms of action, monitor chronic toxicity, and study transport across biological barriers, all within a flexible service framework tailored to their specific program needs.
Liver-on-Chip
Study drug-induced liver injury, metabolism, and chronic toxicity using dynamically perfused liver models.
Multi-Organ Connections
Combine liver and other organ compartments using recirculating perfusion to capture systemic interactions.
Lung-on-Chip
Model lung barrier function and aerosol or systemic drug exposure in microfluidic chips with controlled pressure.
Multi-Organ Connections
Use membrane chips for permeability, transport, and co-culture experiments across apical-basal compartments.
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