Spleen Targeted Premade FLuc mRNA Lipid Nanoparticle 
 
Spleen Targeted Premade FLuc mRNA Lipid Nanoparticle is a LNP loaded with Firefly Luciferase mRNA (m1Ψ) has spleen specific targeting effect after systemic administration.  
 
The LNP is formulated with main ionizable lipid of SM102 and anionic lipid 18PA.  
 
The payload FLuc mRNA (m1Ψ) has all the U bases 100% modified with N1-methyl-pseudouridine (m1Ψ). This LNP formulation showed enhanced delivery of spleen organ after in vivo delivery.
 
Payload:
FLuc mRNA (m1Ψ)
Formulation:
Ionizable lipid, DSPC, PEG-2000 DMG, Cholesetrol 
Storage Buffer:
10% Sucrose in PBS
Appearance:
Clear and colorless
Storage:
-20° C or below. We recommend to minimize freeze-thaw cycles to preserve LNPs integrity.
Shipping:
Dry ice
Handling:
Avoid freeze and thaw
Concentration:
~0.1 mg/mL
Stock:                                              
On-demand
 
Special formulation and other requirements are available up request.   Contact us.
 
For Research Use Only. Not for use in diagnostic procedures.