Cre mRNA (Cap1, m1Ψ)
 
This Cre mRNA encodes Cre recombinase, a tyrosine recombinase that catalyzes site-specific recombination between two loxP sites in DNA, supporting conditional gene knockout, gene knock-in, and reporter activation in Cre-loxP research systems.
 
Designed for efficient in vitro transfection, PreciGenome’s Cre mRNA provides a high-quality, ready-to-use alternative to plasmid- or protein-based Cre delivery. Its Cap1-capped, poly(A)-tailed, m1Ψ-modified design supports high translation efficacy while minimizing innate immune activation — a research-grade tool for Cre-loxP conditional gene editing and lineage-tracing studies.
 
Product Features
Cap1 structure for enhanced translation efficiency.
m1Ψ (N1-Methylpseudouridine) modified nucleotide to reduce innate immune activation and enhance mRNA stability.
Poly(A) tail for stable expression and enhanced translation initiation.
 
Product Specifications
Form: Liquid
Concentration: 1 mg/mL
mRNA Length: 1282 nucleotides
Buffer: 1 mM Sodium Citrate, pH 6.4
Storage: Store at –40 °C or below.
Shipping Method: Dry ice
 
Quality Control
Appearance: Colorless liquid
RNA Purity: ≥ 95%
OD260/OD280: 1.70–2.30
Endotoxin: < 10 EU/mg
pH: 6.0–7.0
For research use only.

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