LipidFlex™ Lipid Nanoparticle Formulation Kit, 3-Lipid Mix and Ionizable Lipid
 
The LipidFlex™ Lipid Nanoparticle Formulation Kit is a comprehensive solution designed for researchers developing lipid nanoparticles (LNPs) for nucleic acid delivery applications. This innovative kit features an easy-to-mix 3-component lipid mixture paired with a separate cationic/ionizable lipid component, providing maximum flexibility in formulation development. The system enables precise control over lipid ratios, allowing researchers to optimize their LNP formulations for nucleic acid and protein (such as mRNA, siRNA, circRNA, DNA, peptide etc.) encapsulation and delivery requirements.
 
Key Features
Flexible Formulation Control: Adjustable cationic/ionizable lipid ratios to meet specific research needs
Buffer System Compatibility: Compatible with various buffer systems for diverse experimental conditions
Optimizable N/P Ratios: Flexible nucleic acid to lipid ratios for enhanced encapsulation
Consistent Particle Size: Achieves uniform nanoparticles in the 40-200 nm range
Low Polydispersity: PDI values between 0.05-0.2 ensure narrow size distribution
High Encapsulation Efficiency: >80% standard efficiency (>95-99% under optimized conditions)
Multiple Ionizable Lipid Options: Choose from MC3, SM-102, LP-01, or ALC-0315
Superior Performance: High transfection efficiency, protein expression, and cell viability
Time-Efficient: Streamlined synthesis process for rapid formulation development
 
Applications
mRNA vaccine development and research
Gene therapy vector preparation
siRNA delivery system development
Antisense oligonucleotide encapsulation
CRISPR/Cas9 delivery research
Therapeutic nucleic acid formulation studies
Drug delivery system optimization
Biomedical research applications
 
Product Specifications
Kit Components:
Component
Size
Concentration
Ionizable Lipid (MC3, SM-102, LP-01, or ALC-0315)
25 mg
-
3-Lipid Mix (Structural Lipid/Cholesterol/Stabilizer)
1000 μL
30 mM
 
Storage & Handling Instructions
Storage Temperature: -20°C or below for all components
Stability: Stable for 12 months when stored properly at -20°C
Handling: Allow components to reach room temperature before use
Avoid: Repeated freeze-thaw cycles
Protection: Store away from light and moisture
Thawing: Thaw components gently at room temperature or 4°C
 
Custom Solutions
PreciGenome offers comprehensive custom solutions to meet your specific research requirements:
Custom Lipid Ratios: Tailored formulations based on your application needs
Alternative Ionizable Lipids: Access to additional ionizable lipid options
Bulk Quantities: Scaled production for large-scale studies
Custom Buffer Systems: Formulations compatible with your preferred buffer conditions
Technical Consultation: Expert guidance for formulation optimization
Custom Kit Configurations: Modified kit compositions to suit specific research goals
 
Important Notes
For Research Use Only. This product is not for human or veterinary use.
For technical support, custom formulations, or bulk orders, please contact us.