LipidFlex™ Lipid Nanoparticle Formulation Kit, 3-Lipid Mix (no Ionizable Lipid)
LipidFlex™ is an advanced 3-component lipid mixture designed for versatile nanoparticle formulation applications. This ready-to-use kit provides researchers with a flexible platform for generating both liposomes and lipid nanoparticles (LNPs) for diverse encapsulation needs. The formulation can be directly used for small molecule encapsulation in liposome applications or combined with various cationic/ionizable lipids to create LNPs for nucleic acid and protein (such as mRNA, siRNA, circRNA, DNA, peptide etc.) delivery systems.
Key Features
Versatile Compatibility: Works seamlessly with different cationic/ionizable lipids including MC3, SM-102, LP-01, ALC-0315, and others
Flexible Formulation Options:
Adjustable cationic/ionizable lipid ratios
Compatible with various buffer systems
Customizable N/P ratios for optimal performance
High Performance: Consistently produces nanoparticles with 40-200 nm particle size and low polydispersity index (PDI 0.05-0.2)
Superior Encapsulation Efficiency: Achieves >80% encapsulation efficiency under standard conditions (>95-99% under optimized conditions)
Ready-to-Use Convenience: Pre-formulated mixture eliminates preparation time and reduces batch-to-batch variability
Applications
Liposome Formation: Direct use for small molecule encapsulation and drug delivery applications
Lipid Nanoparticle (LNP) Generation: When combined with ionizable lipids for:
mRNA delivery and vaccine development
circRNA encapsulation
siRNA therapeutic applications
DNA transfection studies
Protein delivery systems
Research Applications: Gene therapy research, drug delivery studies, and pharmaceutical development
Product Specifications
| Parameter | Specification |
|---|---|
| Components | Structural lipid/Cholesterol/Stabilizer |
| Product Size | 1,000 μL |
| Lipid Concentration | 30 mM |
Storage & Handling Instructions
Storage Temperature: -20°C or below
Stability: Stable for 12 months when stored properly at -20°C
Preparation: Ready-to-use formulation requires no additional preparation steps
Custom Solutions
PreciGenome offers comprehensive support for your specific research needs:
Custom Formulations: Tailored lipid compositions to meet your specific application requirements
Bulk Orders: Large-scale production available for extensive research projects
Technical Consultation: Expert guidance on formulation optimization and application-specific protocols
Protocol Development: Customized protocols for your specific delivery applications
Important Notes
For Research Use Only. This product is not for human or veterinary use.
For technical support, custom formulations, or bulk orders, please contact us.
LipidFlex™ Lipid Nanoparticle Formulation Kit, 3-Lipid Mix (no Ionizable Lipid)
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評論
This is an excellent kit for anyone working with lipid nanoparticles. The LipidFle kit is incredibly user-friendly and highly effective. I was particularly impressed with its versatility, as it's compatible with different lipid ratios and buffer systems. The high encapsulation efficiency, which can reach over 95%, is a major advantage, ensuring that our nucleic acid payloads are delivered successfully. The ability to consistently produce nanoparticles within the desired size range.