LipidFlex™ Antibody Conjugation LNP Formulation Kit
 
The LipidFlex™ Antibody Conjugation LNP Formulation Kit is a versatile platform designed for researchers seeking to develop targeted lipid nanoparticle (LNP) delivery systems. This kit enables you to encapsulate your own payload—such as nucleic acids or small molecules—while conjugating antibodies of your choice for precise tissue or cell-specific delivery.
 
Antibody-conjugated LNPs represent a next-generation delivery modality with significant potential in fields such as cancer therapy and gene therapy. By coupling antibody specificity with optimized LNP formulations, researchers can achieve improved targeting, enhanced transfection efficiency, and minimized off-target effects. This system incorporates clinically relevant lipid components and a straightforward workflow that accelerates experimental testing and development.
 
Key Features
Ready-to-use lipid mix optimized for targeted LNP formulation
Enables both payload encapsulation and antibody conjugation
Narrow particle size distribution for reproducible results
High mRNA transfection efficiency and protein expression levels
Excellent cell viability profile compared to traditional methods
Time-efficient synthesis process suitable for research-scale studies
 
Applications
Targeted Cancer Therapy: Conjugate antibodies to enable selective delivery of cytotoxic payloads to tumor cells.
Gene Therapy Research: Deliver mRNA or gene-editing tools specifically to non-hepatic cell populations.
Drug Delivery Studies: Evaluate encapsulated small-molecule or protein therapeutics in targeted delivery contexts.
Vaccine Development: Extend beyond conventional LNP performance for next-generation vaccine platforms.
 
Product Specifications
 
Kit Contents:
Component                                          
Quantity           
Storage
Antibody Conjugation Lipid Mix
1 mL
-20°C
Ionizable Lipid*
25 mg
-20°C
TCEP (0.5M)
1 mL
4°C
 
*Ionizable lipid options available: MC3, SM-102, LP-01, ALC-0315
 
Storage & Handling Instructions
Store the lipid mix and ionizable lipid at -20°C or below. Avoid repeated freeze-thaw cycles.
Store TCEP at 4–8°C. Do not freeze.
Thaw reagents on ice prior to use and handle under sterile conditions to minimize contamination.
Ensure all components are equilibrated to working temperature before starting formulation.
 
Custom Solutions
At PreciGenome, we understand that research requirements vary. We offer comprehensive customization options for this product:
Alternative Targeting Antibodies: Custom antibody conjugation for different cell surface markers
Payload Modifications: Alternative mRNA sequences, reporters, or therapeutic genes
Formulation Adjustments: Modified lipid compositions or concentrations
Scale Options: Various volume and concentration specifications
Buffer Systems: Alternative storage and working buffers
Bulk Manufacturing: Large-scale production for extensive studies
Our technical team works closely with researchers to develop tailored solutions that meet specific experimental needs and research objectives.
 
Important Notes
For Research Use Only. This product is not for human or veterinary use.
 
For technical support, custom formulations, or bulk orders, please contact us.
Performance may vary depending on cell type, experimental conditions, and handling procedures
Optimal transfection conditions should be determined empirically for each specific application
Product specifications are subject to batch-specific variations; refer to individual Certificate of Analysis
Users should validate targeting efficiency and expression levels in their specific experimental systems